Clinical Frailty Scale
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Frailty is a state of increased vulnerability to poor resolution of homoeostasis after a stressor event, which increases the risk of adverse outcomes(1). It can ... 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Frailty&COVID-19:why,what,how,where&when?Pleasenote:**TheCFShasnotbeenwidelyvalidatedinyoungerpopulations(below65yearsofage),orinthosewithlearningdisability.Itmaynotperformaswellinpeoplewithstablelongtermdisabilitysuchascerebralpalsy,whoseoutcomesmightbeverydifferentcomparedtoolderpeoplewithprogressivedisability.Wewouldadvisethatthescaleisnotusedinthesegroups.However,theguidanceonholisticassessmenttodeterminethelikelyrisksandbenefitsofcriticalcaresupport,andseekingcriticalcareadvicewherethereisuncertainty,isstillrelevant.**Why?RapidNICEguidanceproducedinresponsetotheCOVIDoutbreakclearlyoutlinestheimportanceofidentifyingandgradingfrailtyusingtheClinicalFrailtyScale.Thepurposeistoidentifypatientswhoareatincreasedriskofpooroutcomesandwhomaynotbenefitfromcriticalcareinterventions.What?Frailtyisastateofincreasedvulnerabilitytopoorresolutionofhomoeostasisafterastressorevent,whichincreasestheriskofadverseoutcomes(1).ItcanbeassessedquicklyandsimplyusingtheClinicalFrailtyScale(Appendix1).Frailtyidentificationshouldtakenomoretheoneminute(2);themoreyouusethescale,thequickeritwillbecome.TheCFSisareliablepredictorofoutcomesintheurgentcarecontext(Appendix2)(3-9);criticalcarespecificoutcomesaresummarisedinAppendix3.Likeanydecisionsupporttool,isnotperfectandshouldnotbeusedinisolationtodirectclinicaldecisionmaking.Itwillsensitiseyoutothelikelyoutcomesingroupsofpatients,butclinicaldecisionmakingwithindividualpatientsshouldbeundertakenthroughamoreholisticassessment,usingtheprinciplesofshareddecisionmaking.How?TheCFScanbeundertakenbyanyappropriatelytrainedhealthcareprofessional(doctor,nurse,healthcareassistant,therapistetc.)withtrainingandsupport.Askthepatientortheircarer/nextofkin/paramedics/carehomestaffwhattheircapabilitywasTWOweeksago.DONOTbaseyourassessmentonhowthepatientappearsbeforeyoutoday.DecisionmakersusingtheCFStoinformclinicalmanagementMUSTcheckthescoretoensurethatitisaccurate.DObecarefulaboutdifferentiatingbetweenCFS6and7:CFS6(needhelpwithoutdooractivitiesandsomehelpwithbasicactivities)–allcausemortalityduringadmissiontoacutehospital=6%CFS7(completelydependentforpersonalcare)–allcausemortalityduringadmissiontoacutehospital=11%When?TheCFSshouldbeassessedatEDtriage,oranyfirstpointofcontactwithacutecare(includingbyparamedics),alongsideEarlyWarningScores.Itshouldbereassessedaftertwoweeksifclinicallyrelevant.UsingCFSinpracticeDOrememberthattheCFShasonlybeenvalidatedinolderpeople;ithasnotbeenwidelyvalidatedinyoungerpopulations(below65yearofage),orinthosewithlearningdisability.Itmaynotperformaswellinpeoplewithstablelongtermdisabilitysuchascerebralpalsy,whoseoutcomesmightbeverydifferentcomparedtoolderpeoplewithprogressivedisability.WewouldadvisethattheCFSisnotusedinthesegroups.However,theguidanceonholisticassessmenttodeterminethelikelyrisksandbenefitsofcriticalcaresupport,andseekingcriticalcareadvicewherethereisuncertainty,isstillrelevant.Askthepatient,theircarer/nextofkin/paramedics/carehomestaffwhatthepatient’scapabilitywasTWOweeksago.TheassessmentshouldNOTbebasedonhowthepatientappearsbeforeyoutoday.DecisionmakersusingtheCFStoinformclinicalmanagementMUSTcheckthescoretoensurethatitisaccurate.TOPTIPSTOHELPYOUUSETHECFS ProfessorKenRockwoodandcolleagueshavewrittenapaperonCOVID-19,frailtyandlong-termcare,andthepotentialimplicationsforpolicyandpractice,whichcanbefoundhere.AliceWarren,StaffNurseED,LeicesterRoyalInfirmaryAnujaChalishazar,JuniorDoctorED,LeicesterRoyalInfirmaryJayBanerjee,ConsultantinEmergencyMedicineED,LeicesterRoyalInfirmaryProfessorKenRockwoodProfessorofMedicine,DalhousieUniversityAppendix1:clinicalfrailtyscaleTheClinicalFrailtyScalewasdevelopedatDalhousieUniversityinHalifax,NovaScotiaCanada.Thelicenseisfreeforresearch,educational,andnot-for-profithealthcare.Usersareaskedtosignaformagreeingnottochangeorcommercializeit.request/correspondencecanbesenttotheGeriatricMedicineResearchUnitgmru@dal.ca Appendix2:Outcomesinacutecare(NOTCOVIDspecific)associatedwithfrailty Beloware(unpublished)datadisplayingthetimetodeathfromEDattendancefordifferentfrailtyscores,overtwoyears.Figure1Kaplan-MeiersurvivalplotfortimefromEDarrivaltodeath,byCFScategory,nr=notrecorded: Viewfullsize Appendix3:CriticalcareoutcomesassociatedwithfrailtyFrailtymeasuredusingtheCFSorFrailtyIndexisassociatedwithhigherin-hospital(relativerisk(RR)1.7)andlong-termmortality(RR1.5)(10).Frailpatientswerelesslikelytobedischargedhomethanfitpatients(RR0.6)(11).Additionalstudiesundertakensincethesereviewssupporttheimportanceoffrailtyasaprognosticmarker(Table1).Table1OutcomesfromICUusingfrailtyasapredictor Viewfullsize References1.CleggA,YoungJ,IliffeS,etal.Frailtyinelderlypeople.Lancet(London,England)2013;381:752-62.doi:10.1016/S0140-6736(12)62167-92.ElliottA,PhelpsK,RegenE,etal.IdentifyingfrailtyintheEmergencyDepartment-feasibilitystudy.AGEANDAGEING2017;46(5):840-45.doi:10.1093/ageing/afx0893.CardonaM,LewisET,KristensenMR,etal.PredictivevalidityoftheCriSTALtoolforshort-termmortalityinolderpeoplepresentingatEmergencyDepartments:aprospectivestudy.EurGeriatrMed2018;9(6):891-901.doi:10.1007/s41999-018-0123-6[publishedOnlineFirst:2018/12/24]4.Romero-OrtunoR,WallisS,BiramR,etal.Clinicalfrailtyaddstoacuteillnessseverityinpredictingmortalityinhospitalizedolderadults:Anobservationalstudy.EurJInternMed2016;35:24-34.doi:10.1016/j.ejim.2016.08.033[publishedOnlineFirst:2016/09/07]5.WallisSJ,WallJ,BiramRW,etal.Associationoftheclinicalfrailtyscalewithhospitaloutcomes.QJM2015;108(12):943-9.doi:10.1093/qjmed/hcv066[publishedOnlineFirst:2015/03/18]6.BasicD,ShanleyC.Frailtyinanolderinpatientpopulation:usingtheclinicalfrailtyscaletopredictpatientoutcomes.JournalofAgingandHealth2015;27:670-85.doi:10.1177/08982643145582027.ProvencherV,SiroisM-J,OuelletM-C,etal.DeclineinActivitiesofDailyLivingAfteraVisittoaCanadianEmergencyDepartmentforMinorInjuriesinIndependentOlderAdults:AreFrailOlderAdultswithCognitiveImpairmentatGreaterRisk?JournaloftheAmericanGeriatricsSociety2015;63(5):860-68.doi:10.1111/jgs.133898.HubbardRE,PeelNM,SamantaM,etal.DerivationofafrailtyindexfromtheinterRAIacutecareinstrument.BMCGeriatr2015;15(27):015-0026.9.KahlonS,PedersonJ,MajumdarSR,etal.Associationbetweenfrailtyand30-dayoutcomesafterdischargefromhospital.CMAJ:CanadianMedicalAssociationjournal=journaldel'Associationmedicalecanadienne2015;187:799-804.doi:10.1503/cmaj.15010010.DarvallJN,GregorevicKJ,StoryDA,etal.Frailtyindexesinperioperativeandcriticalcare:Asystematicreview.ArchivesofGerontology&Geriatrics2018;79:88-96.11.MuscedereJ,WatersB,VaramballyA,etal.Theimpactoffrailtyonintensivecareunitoutcomes:asystematicreviewandmeta-analysis.IntensiveCareMedicine2017;43(8):1105-22.12.DarvallJN,BellomoR,PaulE,etal.FrailtyinveryoldcriticallyillpatientsinAustraliaandNewZealand:apopulation-basedcohortstudy.MedicalJournalofAustralia2019;211(7):318-23.13.GuidetB,deLangeDW,BoumendilA,etal.Thecontributionoffrailty,cognition,activityofdailylifeandcomorbiditiesonoutcomeinacutelyadmittedpatientsover80yearsinEuropeanICUs:theVIP2study.IntensiveCareMedicine2020;46(1):57-69.14.LanglaisE,NesselerN,LePabicE,etal.DoestheclinicalfrailtyscoreimprovetheaccuracyoftheSOFAscoreinpredictinghospitalmortalityinelderlycriticallyillpatients?Aprospectiveobservationalstudy.JournalofCriticalCare2018;46:67-72.15.ZengA,SongX,DongJ,etal.MortalityinRelationtoFrailtyinPatientsAdmittedtoaSpecializedGeriatricIntensiveCareUnit.JournalsofGerontologySeriesA-BiologicalSciences&MedicalSciences2015;70(12):1586-94.16.ShearsM,TakaokaA,RochwergB,etal.Assessingfrailtyintheintensivecareunit:Areliabilityandvaliditystudy.JournalofCriticalCare2018;45:197-203.17.Silva-ObregonJA,Quintana-DiazM,Saboya-SanchezS,etal.Frailtyasapredictorofshort-andlong-termmortalityincriticallyilloldermedicalpatients.JournalofCriticalCare2020;55:79-85.
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