Invasive Ductal Carcinoma (IDC) & Ductal Carcinoma In Situ ...

Invasive ductal carcinoma (IDC) accounts for about 80% of all invasive breast cancers in women and 90% in men. It begins in the cells of a milk ... MenuMedicalReferenceNewsArchiveBreastCancerHomeNewsReferenceSlideshowsBreastCancerCommunityMedicationsFindanOncologistOverview&FactsRisks&PreventionSymptoms&SignsDiagnosis&TestsBreastCancerTypesYourBreastCancerCareTeamBreastCancerTreatmentLiving&ManagingRemission&RecurrenceAdvancedBreastCancerSupport&ResourcesAllGuideTopicsBook:TakeControlofYourCancerRiskHairLoss:12WaystoHandleItBreastReconstructionSurgeryClinicalTrialsBreastCancer&WeightCancerGuideA-ZMoreRelatedTopicsCancerBreastCancerBreastCancerGuideMenuWhatIsDuctalCarcinoma?WhatIsInvasiveDuctalCarcinoma?SymptomsofInvasiveDuctalCarcinomaInvasiveDuctalCarcinomaDiagnosisInvasiveDuctalCarcinomaStagesInvasiveDuctalCarcinomaTreatmentWhatisDuctalCarcinomainSitu(DCIS)?WhatAretheSymptomsofDuctalCarcinomainSitu?HowIsDuctalCarcinomainSituDiagnosed?HowIsDuctalCarcinomainSituTreated?MoreWhatIsDuctalCarcinoma?Ductalcarcinomaisacommontypeofbreastcancerthatstartsincellsthatlinethemilkducts,whichcarrybreastmilktothenipple.Therearetwotypes:Invasiveductalcarcinoma(IDC)Ductalcarcinomainsitu(DCIS),alsocalledintraductalcarcinomaThesymptoms,diagnosis,andtreatmentsforeacharedifferent.WhatIsInvasiveDuctalCarcinoma?Invasiveductalcarcinoma(IDC)accountsforabout80%ofallinvasivebreastcancersinwomenand90%inmen.Itbeginsinthecellsofamilkduct,thenitgrowsthroughtheductwallsandintothesurroundingbreasttissue.Itcanalso spreadtootherpartsofyourbody.SymptomsofInvasiveDuctalCarcinomaInvasiveDuctalCarcinomasymptomsinclude:AlumpinyourbreastThickenedbreastskinRashorrednessonyourbreastSwellinginyourbreastNewpaininyourbreastDimplingonyourbreastortheskinofyournippleNipplepainInvertednippleNippledischargeLumpsunderyourarmChangestoyourbreastornipplethataredifferentfromtheonesyouhavewithyourperiod InvasiveDuctalCarcinomaDiagnosisIDCisusuallyfoundastheresultofanabnormalmammogram.Todiagnosecancer,you’llgetabiopsytocollectcellsforanalysis.Thedoctorwillremoveabitoftissuetolookatunderamicroscope.Theycanmakeadiagnosisfromthebiopsyresults.Ifthebiopsyconfirmsyouhavecancer,you’lllikelyhavemoreteststoseehowlargethetumorisandifithasspread:CTscan.It'sapowerfulX-raythatmakesdetailedpicturesinsideyourbody.PETscan.Thedoctorinjectsaradioactivesubstancecalledatracerintoyourarm.Ittravelsthroughyourbodyandgetsabsorbedintothecancercells.TogetherwithaCTscan,thistestcanhelpfindcancerinlymphnodesandotherareas.MRI.Itusesstrongmagnetsandradiowavestomakepicturesofthebreastandotherstructuresinsideyourbody.Bonescan.Thedoctorinjectsatracerintoyourarm.Theytakepicturestofindoutifcancerhastraveledtoyourbones.ChestX-ray.Ituseslowdosesofradiationtomakepicturesoftheinsideofyourchest. InvasiveDuctalCarcinomaStagesResultsfromthesetestswillshowthestageofyourcancer.Stagingisthenamefortheprocessdoctorsusetofigureoutifandhowfarbreastcancerhasspread.Knowingthestagewillhelpguideyourtreatment.Doctorscanusetheresultsfromyourdiagnostictestingtogatherinformationaboutthetumor.TheygroupitbyasystemknownasTNM:Tumor(T):Howlargeistheprimarytumor?Whereisit?Node(N):Hasthetumorspreadtoyourlymphnodes?Where?Howmuch?Metastasis(M):Hasthecancerspreadtootherbodyparts?Whichones?Howmuch?Tostageyourcancer,yourdoctorcombinestheTNMresultswiththetumorgrade(howyourtumorcellsandtissuelookunderamicroscopeandyourhormonereceptorstatus(ifthecancercellshaveproteinsthatrespondtothehormonesestrogenorprogesteroneandyourHER2status(whetheryourcancerisaffectedbytheHER2gene).Stagesinclude:Stage0:Thisisnoninvasivecancer.It’sonlyintheductsandhasn’tspread(Tis,N0,M0).StageIA:Thetumorissmallandinvasive,butithasn’tspreadtoyourlymphnodes(T1,N0,M0).StageIB:Cancerhasspreadtothelymphnodes.It’slargerthan0.2mmbutlessthan2mminsize.There’seithernosignofatumorinthebreastorthereis,butit’s20mmorsmaller(T0orT1,N1,M0).StageIIA:Anyoneofthese:There’snosignofatumorinthebreast.Thecancerhasspreadtobetween1and3underarmlymphnodes,butnottoanydistantbodyparts(T0,N1,M0).Thetumoris20mmorsmallerandhasspreadtounderarmlymphnodes(T1,N1,M0).Thetumorisbetween20mmand50mmbuthasn’tspreadtonearbynodes(T2,N0,M0).StageIIB:Eitheroftheseconditions:Thetumorisbetween20mmand50mmandhasspreadtoonetothreeunderarmlymphnodes(T2,N1,M0).Thetumorislargerthan50mmbuthasn’tspreadtounderarmlymphnodes(T3,N0,M0).StageIIIA:Eitheroftheseconditions:Cancerofanysizehasspreadtofourtonineunderarmlymphnodesorthoseunderyourchestwall.Ithasn’tspreadtootherbodyparts(T0,T1,T2orT3,N2,M0).Atumorlargerthan50mmhasspreadtoonetothreenearbylymphnodes(T3,N1,M0).StageIIIB:Thetumor:HasspreadtothechestwallHascausedswellingorbreastsoresHasbeendiagnosedasinflammatorybreastcancerMayormaynothavespreadtouptoninelymphnodesunderyourarmorbeneaththechestwallHasn’tspreadtootherbodyparts(T4;N0,N1orN2;M0)StageIIIC:Atumorofanysizethathasspreadto10ormorenearbylymphnodes,breastlymphnodes,and/orlymphnodesunderthecollarbone.Ithasn’tspreadtootherbodyparts(anyT,N3,M0).StageIV(metastatic):Thetumorcanbeanysizeandhasspreadtootherorgans,likeyourbones,lungs,brain,liver,distantlymphnodes,orchestwall(anyT,anyN,M1).Between5%and6%ofthetime,metastaticcancerisdiscovereduponfirstdiagnosis.Yourdoctormaycallthisdenovometastaticbreastcancer.Moreoften,it’sfoundafterapreviousdiagnosisofearlybreastcancer.Recurrent:Thisiscancerthatcomesbackaftertreatment.Itcanbelocal,regional,and/ordistant.Ifyourcancerreturns,you’llgetanotherroundofteststolearnabouttheextentoftherecurrence.They’llbesimilartothoseatyouroriginaldiagnosis.InvasiveDuctalCarcinomaTreatmentMostwomenwithIDChavesurgerytoremovethecancer.Thetreatmentoptionsareusually:Lumpectomy:Thesurgeononlyremovesthetumorandabitofthetissuearoundittohelpmakesureallthecancercellshavebeenremoved.Youmighthearitcalledbreast-conservingsurgeryMastectomy:Thesurgeonremovesanentirebreast.Whichoneyougetdependsonthesizeofyourtumorandhowmuchithasspreadthroughoutyourbreastandsurroundinglymphnodes.Inadditiontosurgery,othertreatmentsmayinclude:Radiation:Thisusuallyfollowsyoursurgery.Hormonetherapy:You’llgetitifyourcancerishormonereceptor-positive(meaningestrogenhelpsitgrow).Thesedrugsblockorlowertheamountofestrogeninyourbody.Chemotherapy:Thesemedicationstargetcancercellsthroughoutyourbody.DoctorsmayalsouseItbeforesurgerytoshrinktumorsandaftertokillanycancercellsleftbehind.Targetedtherapy:Thesemedicationsblockcancercellgrowth.Youmightgetthemalongwithchemotherapy.Youmightgetonetreatmentoracombination.WhatisDuctalCarcinomainSitu(DCIS)?DuctalCarcinomainSitu(DCIS),alsoknownasintraductalcarcinoma,accountsforoneofeveryfivenewbreastcancerdiagnoses.It'sanuncontrolledgrowthofcellswithinthebreastducts.It’snoninvasive,meaningithasn’tgrownintothebreasttissueoutsideoftheducts.Thephrase"insitu"means"initsoriginalplace."DCISistheearlieststageatwhichbreastcancercanbediagnosed.It'sknownasstage0breastcancer.Thevastmajorityofwomendiagnosedwithitcanbe cured.Eventhoughit’snoninvasive,itcanleadtoinvasivecancer.It'simportantthatwomenwiththediseasegettreatment.Researchshowsthattheriskofgettinginvasivecancerislowifyou’vebeentreatedforDCIS.Ifitisn’ttreated,30%to50%of womenwithDCISwillgetinvasivecancer.TheinvasivecancerusuallydevelopsinthesamebreastandinthesameareaaswheretheDCIShappened.WhatAretheSymptomsofDuctalCarcinomainSitu?DCISusuallyhasnosymptoms.Mostofthetime,it’sdiagnosedbyamammogram.HowIsDuctalCarcinomainSituDiagnosed?About80%ofcasesarefoundbymammograms.Onthemammogram,itappearsasashadowyarea.IfyourmammogramsuggeststhatyoumayhaveDCIS,yourdoctorshouldorderabiopsytoanalyzethecellsandconfirmthediagnosis.BiopsiesforDCISaretypicallydoneusingneedlestoremovetissuesamplesfromthebreast.IfyouhaveDCIS,yourdoctormaydomoreteststogatherinformationaboutyourcancer.ThesetestsmayincludeanultrasoundorMRI.Basedontheresultsofvarioustests,yourdoctorwillbeabletotellthesizeofyourtumorandhowmuchofyourbreastisaffectedbythecancer.HowIsDuctalCarcinomainSituTreated?Notwopatientsarethesame.Yourdoctorwillcustomizeyourtreatmentplanbasedonyourtestresultsandmedicalhistory.Amongotherthings,yourdoctorwillconsider:TumorlocationTumorsizeAggressivenessofthecancercellsYourfamilyhistoryofbreastcancerResultsoftestsforagenemutationthatwouldincreasetheriskofbreastcancerMostwomenwithDCISdon'thavethebreastremovedwithamastectomy.Instead,theyhavealumpectomy.Mostcommonisalumpectomyfollowedbyradiation.Thesurgeonremovesthecancerandasmallareaofhealthytissuearoundit.Lymphnodesunderthearmdon’tneedtoberemovedastheyarewithothertypesofbreastcancer.Afteralumpectomy,radiationcutsthechancesthatthecancerwillcomeback.Ifcancerdoesreturn,it’scalledrecurrence.Somewomenmayopttohavealumpectomyonly.Discusstherisksofnothavingradiationwithyourdoctorbeforedecidingagainstit.Youandyourdoctorsmaydecidethatamastectomytoremovethebreastisthebestcourseoftreatmentifyouhaveanyofthefollowing:AstrongfamilyhistoryofbreastcancerAgenemutationthatmakeshavingbreastcancermorelikelyVerylargeareasofDCISDCISlesionsinmultipleareasthroughoutyourbreastNotbeingabletolerateradiationtherapyYouandyourtreatmentteammayalsoconsidertheuseofhormonetherapyifthecancertestspositiveforhormonereceptors.Itcancutthechanceofgettinganotherbreastcancer.BreastCancerGuideOverview&FactsRisks&PreventionSymptoms&SignsDiagnosis&TestsBreastCancerTypesYourBreastCancerCareTeamBreastCancerTreatmentLiving&ManagingRemission&RecurrenceAdvancedBreastCancerSupport&ResourcesAllGuideTopicsChemo:3ThingsYouNeedtoKnowComplementaryTreatmentsforCancerEverydayHabitstoLowerBreastCancerRiskEatingWellDuringBreastCancerTreatmentBreastCancer'sLinktoBoneMetastasisDietTipstoPreventBreastCancerInvasiveDuctalCarcinoma&DuctalCarcinomaInSituDuctalLavagetoDetectBreastCancerLumpectomy(PartialMastectomy)UsingMammogramstoDetectBreastCancerRiskFactorsforBreastCancerBreastCancerWhatAretheStagesandGradesofBreastCancer?BreastCancer-DuctalCarcinomaTopicsAVisualGuidetoBreastCancerFrommammogramstolivingaftertreatment.DealingWithBreastCancer?Getanswerstoyourquestions.BreastCancerScreeningThe3latesttipstoknow.CancerSideEffectsAndhowtobesttreatthem.VIDEOBreastCancer:What'sWatchfulWaiting?ArticleLivingWellWithMetastaticBreastCancerArticleMammogramScreeningGuidelinesArticleWarningSignsofBreastCancerArticleBreastCancer:StepstoReduceYourRiskQUIZAntiperspirants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